“Mass Cytometry in Clinical Research: Application to Leukemia and Immune Monitoring”
Gregory Behbehani, MD, PhD
Assistant Professor of Internal Medicine
The Ohio State University
Greg Stelzer, PhD
Director of Mass Cytometry Market Development
Mass cytometry enables the simultaneous measurement of over 40 parameters at single-cell level, expanding on the breadth and depth of cell sample characterization allowed by conventional cytometry. High-dimensional cell surface marker analysis combined with simultaneous measurement of functional parameters allows clinical research samples to be characterized more efficiently and in novel ways including single-tube deep immune profiling, analysis of global differentiation status and measurement of cell cycle state in stem cells.
In this Lunch and Learn session, Greg Behbehani will present comparative analysis of leukemia samples by a research mass cytometry assay and a 10-color flow cytometry assay used in a clinical laboratory, showing that research mass cytometry can generate data highly comparable to that of clinical flow cytometry. Greg Stelzer will describe the new Fluidigm Maxpar® Human Immune Monitoring Panel Kit, a single-tube, pre-titrated 29-marker panel kit for human immune monitoring that comes with access to an automated data analysis solution. Such advances are moving mass cytometry closer to a future role in health care decision making.
For Research Use Only. Not for use in diagnostic procedures.