Corporate Lunch & Learn

"A High Parameter cFluor® Panel for Effective Detection of Aberrant Cells in Acute Myeloid Leukemia"

Jun Deng
Director of Clinical Applications and Reagents

Multiparameter flow cytometry is widely and routinely used in acute myeloid leukemia (AML) diagnosis and residual disease detection and monitoring. Because a high number of markers are required, in conventional flow cytometers, markers are typically split into multiple tubes forcing the use of redundant markers and greater sample volume. With Cytek's Full Spectrum Profiling^TM (FSP^TM) technology, many more markers can be combined into a single tube. We have developed a single-tube 20-color panel for AML analysis using the Cytek® Northern LightsTM CLC (NL-CLC) flow cytometer with increased reagent and sample efficiency. The panel performance in healthy and AML bone marrow samples will be discussed.

“Go Beyond Blood - Synthetic Cells to Advance Data Quality and Reproducibility in Flow Cytometry Assays”

Anh-Tuan Nguyen
Co-Founder and VP

Synthetic biology and artificial cell technology have advanced by leaps and bounds over the past decade, and this emerging technology is addressing long-standing needs in biology research, pharmaceutical development, and clinical science. One outcome of this innovation is the development of synthetic cells as ideal cellular mimic controls for many applications in cell analysis, especially for flow cytometry. At Slingshot, we have developed the FlowCytes platform technology. FlowCytes are granular, semi-transparent synthetic cells with an optical, biochemical, and physical equivalent to that of living human cells. This cutting-edge technology is being applied to solve the needs of flow cytometry research of the future such as spectral analysis, quantitative numeration, and solutions for rare cell phenotypes.