ICCS 2022 | Montreal, QC

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Conference Program

Conference Program

The preliminary program for the 2022 Clinical Cytometry Meeting & Course is posted below. Please check back for updates. All program times are listed in Eastern Time.

COURSE DATES
Friday, October 21 - Sunday, October 23

MEETING DATES
Sunday, October 23 - Tuesday, October 25

Fri - Oct 21

Sat - Oct 22

Sun - Oct 23

Mon - Oct 24

Tue - Oct 25

View Program Details

Monday, October 24th

8:15 - 8:30 AM
Ancillary Event

BUSINESS MEETING
Chair/Organizer: Adam Seegmiller

Ballroom West

8:30 - 11:20 AM
Plenary Session

PLENARY SESSION 2: FLOW CYTOMETRY APPLICATIONS IN PEDIATRIC DISORDERS
Chair/Organizer: Andrea Marcogliese, Ahmad Al-Attar

Ballroom West

8:30

CSI Case:T-LBLL with Aberrant B-cell Markers
Paul Mead.

8:45

Germline Predisposition in Hematolymphoid Neoplasia
Julia Geyer .

9:30

Coffee Break
.

10:00

Down Syndrome-Related Myeloid Neoplasms
Johann Hitzler .

10:40

Flow Cytometry Applications in the Diagnosis and Management of Immunodeficiency Disorders
Sergio Rosenzweig.

11:30 - 1:00 PM
Educational Workshop

MONDAY LUNCHEON WORKSHOP 1: AML MINIMAL MEASURABLE DISEASE DETECTION, THE CHALLENGES, PITFALLS AND SOLUTIONS

3rd Floor - Drummond East

AML Minimal Measurable Disease Detection, the Challenges, Pitfalls and Solutions - Part 1
Sindhu Cherian.

AML Minimal Measurable Disease Detection, the Challenges, Pitfalls and Solutions - Part 2
Wei Wang.

MONDAY LUNCHEON WORKSHOP 2: TECHNICAL AND DIAGNOSTIC CONSIDERATIONS IN EOSINOPHIL, MAST CELL, BASOPHIL, AND PLASMACYTOID DENDRITIC CELL DISORDERS

3rd Floor - Salon 7

Technical and Diagnostic Considerations in Eosinophil, Mast Cell, Basophil, and Plasmacytoid Dendritic Cell Disorders - Part 1
Sanam Loghavi.

Technical and Diagnostic Considerations in Eosinophil, Mast Cell, Basophil, and Plasmacytoid Dendritic Cell Disorders - Part 2
David Ng.

MONDAY LUNCHEON WORKSHOP 3: A HITCHHIKERS’ GUIDE TO CLSI H62

3rd Floor - Drummond Centre

1

A Hitchhikers Guide to CLSI H62 - Part 1
Virginia Litwin.

2

A Hitchhikers Guide to CLSI H62 - Part 2
Teri Oldaker.

MONDAY LUNCHEON WORKSHOP 4: HOW TO IMPROVE YOUR DATA PART 1

3rd Floor - Drummond West

This workshop will cover different methods for sample processing and staining, tips on improving light-chain resolution, optimal preservation, handling and maximizing yields of paucicellular specimens (e.g., CSF), tissue disaggregation, cocktail preparation and QC, antibody titration and lot-to-lot QC.

How to Improve Your Data 1.2
Ahmad Al-Attar.

How to Improve Your Data Part 1.1
Valerie Miller.

1:00 - 4:00 PM
Plenary Session

PLENARY SESSION 3: ARE WE HITTING THE MARKER? PERFORMANCE STANDARDS AND REGULATIONS
Chair/Organizer: Sara Monaghan, Ben Hedley

Ballroom West

1:00

CSI Case
Sarah Blain.

1:15

Hot Topics: College of American Pathologists Accreditation FLO Checklist Items - Part 1
Jolene Cardinali.

1:30

Hot Topics: College of American Pathologists Accreditation FLO Checklist Items - Part 2
William Karlon.

1:45

Questions Raised for Flow Cytometrists Required to Adapt to the EU Regulation on In Vitro Diagnostic Medical Devices 2017/746 (IVDR)
Marie-Christine Bene.

2:15

Coffee Break
.

2:45

Obtaining FDA Investigational Device Exemption (IDE) for an AML Measurable Residual Disease Assay: Overview, Successes and Challenges
Sa Wang.

3:30

Has the VALID Act Become Law? Status Update for the Verifying Accurate, Leading-Edge In Vitro Clinical Test Development Act
Michael Borowitz.

3:55

Q&A
.

4:00 - 5:30 PM
Poster Session

POSTER SESSION 2

Ballroom Central/East

200

Beyond the ISHAGE: Evolving Guidelines for CD34 Enumeration
Ahmad AL-ATTAR¹, D Robert SUTHERLAND². ¹UMass Memorial Health, Worcester, MA, USA.²University of Toronto, Toronto, ON, Canada

201

A High Parameter Panel for Effective Detection of Aberrant Cells in Acute Myeloid Leukemia
Qing Chang, Mark Edinger, Jingyi Chen, Jun Deng. Cytek Biosciences, Inc., Fremont, CA, USA

202

Viable Mononuclear Cell Cryopreservation as a Resource for On-Demand Validation of Rare Markers in Clinical Flow Cytometry
Katarina Czibere¹, Olga Bigun¹, Alexandra Misura¹, Dylan Gowlett-Park¹, Kalpesh Shah², Tariq Hillawi², Julie Collavoli², Nichole Dias², Chloe Chung², Mital Pandya², Dianne Chadwick^{1, 3}, Larissa Liontos^{1, 3, 5}, Signy Chow^{3, 4}, Hubert Tsui^{1, 3, 5}. ¹Sunnybrook Biobank, Department of Laboratory Medicine and Molecular Diagnostics, Precision Diagnostic and Therapeutics Program, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.²Clinical Flow Cytometry, Division of Hematopathology, Department of Laboratory Medicine and Molecular Diagnostics, Precision Diagnostic and Therapeutics Program, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.³Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.⁴Hematology Site Group, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.⁵Division of Hematological Pathology, Department of Laboratory Medicine and Molecular Diagnostics, Precision Diagnostic and Therapeutics Program, Sunnybrook Health Sciences Centre, Toronto, ON, Canada

203

B-Lymphoblastic Leukemia with antigen-shift on relapse post Blinatumomab
George Deeb. Department of pathology and laboratory medicine

204

28-color single tube myeloid analysis for cell of origin and MRD detection
Qi Gao, Jingping Zhang, Xiaotian Sun, Jennifer Goshaw, Jessica Wardrope, Mikhail Roshal. Memorial Sloan-Kettering Cancer Center, New York, NY, USA

205

Evaluation of T-cell Receptor Constant-1 and TRBC ratio in assessing T cell clonality by flow cytometric analysis
Ibrahim R Hajjali¹, Sa Wang², Wei Wang², Fuli Jia², Yun Sawyer¹, Guang Fan¹, Wei Xie¹. ¹Department of Pathology and Laboratory, Oregon Health & Science University, Portland, OR, USA.²Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

206

Quantitative analysis of 10-Color Immunophenotyping assayfollowing serial-diluted leukocyte reduction for use in paucicellular samples.
Malgorzata Kajstura, Tia LaBarge, Andrew Evans, Richard Burack. UNIVERSITY OF ROCHESTER MEDICAL CENTER, Rochester, NY, USA

207

CellMek SPS Instrument Performance: Cellular and Reagent Carryover when using the Cell Wash Module
Brittany N. Kuhl, Xizi Dai, Jessica Ashbaugh, Ernesto Staroswiecki. Research and Development, Beckman Coulter Life Sciences, Miami, FL, USA

208

A rare case transformed from acute monocytic leukemiawith KMT2A-MLLT10 to acute megakaryoblastic leukaemia
Ting Li¹, Ping Wu², Man Chen¹, Minjing Fu¹, Aixian Wang², Hui Wang². ¹Beijing Lu Daopei Hospital, Beijing, China.²Hebei Yanda Lu Daopei Hospital, Langfang, China

209

A Multi-Site Clinical Evaluation of Cytek cFluor 6-Color TBNK-SL Assayon CytekNorthern LightsTM(NL) CLC Cytometers
Jennifer Liu, Decai Li, Ya Guo, Jing Xue, Qing Chen, Wenqing Li, Junwei Xin, Xiaoling Hu, Jun Deng. Cytek Biosciences, Fremont, CA, USA

210

T cell immunophenotypes from 18 patients with query lymphocyte-variant hypereosinophilic syndrome: a case-control comparison
Jack Lofroth¹, XiuQing Wang², Kevin Shopsowitz², Andrew P Weng^{2, 3}, Nadia Medvedev^{2, 4}, Luke Chen^{1, 5}, Xuehai Wang^{1, 2}. ¹Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.²Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.³Division of Hematopathology, BC Cancer, Vancouver, BC, Canada.⁴Division of Hematopathology, Vancouver General Hospital, Vancouver, BC, Canada.⁵Division of Hematology, University of British Columbia, Vancouver, BC, Canada

211

Flow immunophenotyping of cell suspension obtained from bone marrow biopsy needle wash in comparison to bone marrow aspirate: An alternative technique in cases of marrow aspirate dry tap.
Talal Mahdi¹, Michel Leduc¹, Alanna Macleod¹, Carole Gauthier¹, Kim Varas¹, Sophie Xueying ¹, Diane Turpin¹, Katryna Petersen¹, Todd Ogilby¹, Ann Sabourin¹, Amr Rajab². ¹The Ottawa Hospital/University of Ottawa, Ottawa, ON, Canada.²LifeLabs Medical Laboratory Services, Toronto, ON, Canada

212

CD45 negativity is associated with hyperdiploidy and likely predicts a good clinical outcome in pediatric precursor B-cell acute lymphoblastic leukemia
Ruth / E. Morgan, Roxanne Nieder, Sa / T. Truong, Weijie Li. Department of Pathology and Laboratory Medicine, Children's Mercy Hospital, Kansas City, MO, USA

213

Real-world experience of measurable residual disease response and prognosis in acute myeloid leukemia treated with venetoclax and azacitidine
Shin Yeu Ong¹, Nurul Aidah Abdul Halim¹, Si Yun Melinda Tan¹, Yan Chin Tan¹, Dheepa Christopher², Wei Ying Jen³, Christian Gallardo², Angeline Hwee Yim Tan¹, Yeow Kheong Woon¹, Heng Joo Ng¹, Melissa Ooi³, Gee Chuan Wong¹. ¹Singapore General Hospital, Singapore, Singapore.²Tan Tock Seng Hospital, Singapore, Singapore.³National University Cancer Institute, Singapore, Singapore

214

Camelid-derived CD38 Antibody Successfully Circumvents Epitope Blockade by Therapeutic Anti-CD38 Antibody Daratumumab
You-Wen Qian, Joseph Tario. Roswell Park Cancer Center, Buffalo, NY, USA

215

Roles of Monocytes in COVID-19 Inflammation
Eugene V Ravkov¹, Elizabeth Williams², Marc Elgort¹, Adam P Barker¹, Adam M Spivak³, Julio C Delgado¹, Leo Lin¹, Timothy M Hanley¹. ¹ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, UT, USA.²Division of Microbiology and Immunology, University of Utah, Salt Lake City, UT, USA.³Division of Infectious Diseases, University of Utah, Salt Lake City, UT, USA

216

Diagnostic pitfall, an unusual case of NK/T cell lymphoproliferative disorder with aberrant expression of CD20 and kappa light chain
Tanja Skierka, Nashwa Abed, Liqun Yin. Incyte Diagnostic, 13103 E Mansfield Ave, Spokane Valley, WA 99216

217

An optimized slide-sorting method useful to enrich rare cells for downstream fluorescence in situ hybridization study
Xiaotian Sun¹, Dory Londono², Umut Aypar², Yanming Zhang², Qi Gao¹, Mikhail Roshal¹. ¹Hematopathology Service, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.²Cytogenetics Laboratory, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA

218

Evaluation of the impact of standardized 8-color flow cytometry protocols on the diagnostic accuracy of acute leukemias
Rafik Terra¹, Vincent Ãthier², Julie Bergeron¹, Richard LeBlanc¹, Giovanni DâAngelo¹, JosÃ©e HÃ©bert¹, Ariane Morin-Quintal¹, Lambert Busque¹. ¹Division of Hematology, Oncology and Transplantation, Department of Medicine, HÃ´pital Maisonneuve-Rosemont, UniversitÃ© de MontrÃ©al, Montreal, QC, Canada.²Division of Hematology and Oncology, Centre Hospitalier Universitaire de Sherbrooke, UniversitÃ© de Sherbrooke, Sherbrooke, QC, Canada.³Division of Hematology, Oncology and Transplantation, Department of Medicine, HÃ´pital Maisonneuve-Rosemont, UniversitÃ© de MontrÃ©al, Montreal, QC, Canada.⁴Division of Hematology, Oncology and Transplantation, Department of Medicine, HÃ´pital Maisonneuve-Rosemont, UniversitÃ© de MontrÃ©al, Montreal, QC, Canada.⁵Division of Hematology, Oncology and Transplantation, Department of Medicine, HÃ´pital Maisonneuve-Rosemont, UniversitÃ© de MontrÃ©al, Montreal, QC, Canada.⁶Division of Hematology, Oncology and Transplantation, Department of Medicine, HÃ´pital Maisonneuve-Rosemont, UniversitÃ© de MontrÃ©al, Montreal, QC, Canada.⁷Division of Hematology, Oncology and Transplantation, Department of Medicine, HÃ´pital Maisonneuve-Rosemont, UniversitÃ© de MontrÃ©al, Montreal, QC, Canada.⁸Division of Hematology, Oncology and Transplantation, Department of Medicine, HÃ´pital Maisonneuve-Rosemont, UniversitÃ© de MontrÃ©al, Montreal, QC, Canada

219

A case of Mantle cell lymphoma (blastoid variant) with a confusing appearance: How standardized flow cytometry can make a difference!
Rafik Terra, Pascale Dube, Sofiane Benamou, Richard Leblanc. Maisonneuve Rosemont Hospital

221

12 Color Panel ran on BD FACSLyric Flow Cytometer Integrated with the BD FACSDuet Sample Preparation System compared to conventional manual sample processing
Yang Zeng, Brandy Bergher, Aruna Poduri, Michelle McNamara. BD Biosciences, San Jose, CA, USA

222

Multi-site evaluation of fresh and freeze-thawed cord blood using the BD Stem Cell Enumeration Kit on BD FACSLyric and BD FACSCanto II Flow Cytometers
Yang Zeng¹, Maurice O'Gorman², Ruba Hsen², Rakesh Nayyar³, Anubha Purang³, Angela Chen¹. ¹BD Biosciences, San Jose, CA, USA.²Children's Hospital Los Angeles, Los Angeles, CA, USA.³Cytoquest Corporation, Toronto, ON, Canada

5:30 - 6:15 PM
Ancillary Event

ALL COMMITTEE'S MEET AND GREET

3rd Floor - Drummond East

7:00 - 10:00 PM
Social Event

BANQUET DINNER

Off Site